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HOME : 연구활동 : 신성재 교수님


Publication in Scientific Journals (SCI or SCIE, Recent 3 years)
Kwon KW, Lee A, Larsen SE, Baldwin SL, Coler RN, Reed SG, Cho SN, Shin SJ, Long-term protective efficacy with
a BCG-prime ID93/GLA-SE boost regimen against the hyper-virulent Mycobacterium tuberculosis strain K in a mouse
model, 2019 Oct. Accepted in Scientific Reports
Hernandez Pando R*, Shin SJ*, Clark S*, Casonato S, Zambrano MB, Kim H, Boldrin F, Mata Espinoza D, Provvedi R,
Arbues A, Marquina Castillo B, Cioetto Mazzabo L, Barrios Payan J, Martin C, Cho SN, Williams A, Manganelli R.
Construction and characterization of the double unmarked Mycobacterium tuberculosis mutant sigE/fadD26 as a vaccine
candidate, 2019 Oct. Accepted in Infection and Immunity (Co-first authorship)
Kim WS, Yoon JH, Shin MK, Shin SJ. Infection of Dendritic Cells With Mycobacterium avium subspecies hominissuis
Exhibits a Functionally Tolerogenic Phenotype in Response to Toll-Like Receptor Agonists via IL-10/Cox2/PGE2/EP2 Axis,
Frontiers in Microbiology, 2019, 10:1795
Choi HH, Kwon KW, Han SJ, Kang SM, Choi E, Kim A, Cho SN, Shin SJ, A novel PPE39 from Mycobacterium
tuberculosis strain Beijing/K induces Th1 polarization via dendritic cell maturation. Journal of Cell Science,
2019, 5;132(17).
Huh HJ, Kim SY, Jhun BW, Shin SJ*, Koh WJ*, Recent advances in molecular diagnostics and understanding
mechanisms of drug resistance in nontuberculous mycobacterial diseases, Infect Genet Evol.
2019, 72:169-182 (Co-corresponding authorship).
Bellerose MM, Baek SH, Huang CC, Moss CE, Koh EI, Proulx MK, Smith CM, Baker RE, Lee JS, Eum S, Shin SJ,
Cho SN, Murray M, Sassetti CM, Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy,
Mbio, 2019, 30;10(4).
Kim DH, Jhun BW, Moon SM, Kim SY, Jeon K, Kwon OJ, Huh HJ, Lee NY, Shin SJ, Daley CL, Koh WJ, In Vitro
Activity of Bedaquiline and Delamanid against Nontuberculous Mycobacteria, Including Macrolide-Resistant Clinical
Isolates, Antimicrob Agents Chemother, 2019, 25;63(8).
Huh HJ, Kim SY, Shim HJ, Kim DH, Yoo IY, Kang OK, Ki CS, Shin SY, Jhun BW, Shin SJ, Daley CL, Koh WJ, Lee NY,
GenoType NTM-DR Performance Evaluation for Identification of Mycobacterium avium Complex and Mycobacterium
abscessus and Determination of Clarithromycin and Amikacin Resistance, Journal of Clinical Microbiology,
2019, 26;57(8).
Moon SM, Jhun BW, Baek SY, Kim S, Jeon K, Ko RE, Shin SH, Lee H, Kwon OJ, Huh HJ, Ki CS, Lee NY, Chung MJ,
Lee KS, Shin SJ, Daley CL, Koh WJ, Long-term natural history of non-cavitary nodular bronchiectatic nontuberculous
mycobacterial pulmonary disease, Respiratory Medicine, 2019, 151:1-7.
Kim SY, Moon SM, Jhun BW, Kwon OJ, Huh HJ, Lee NY, Lee SH, Shin SJ, Kasperbauer SH, Huitt GA, Daley CL,
Koh WJ, Species Distribution and Macrolide Susceptibility of Mycobacterium fortuitum Complex Clinical Isolates,
Antimicrob Agents Chemother. 2019, 24;63(6).
Kim SY, Jhun BW, Moon SM, Jeon K, Kwon OJ, Huh HJ, Lee NY, Shin SJ, Daley CL, Koh WJ, Genetic mutations in
linezolid-resistant Mycobacterium avium complex and Mycobacterium abscessus clinical isolates, Diagn Microbiol
Infect Dis, 2019, 94(1):38-40.
Kim WS, Kim H, Kwon KW, Cho SN, Shin SJ, Immunogenicity and Vaccine Potential of InsB, an ESAT-6-Like Antigen
Identified in the Highly Virulent Mycobacterium tuberculosis Beijing K Strain, Frontiers in Microbiology, 2019, 10:220
Kwon KW, Choi HH, Han SJ, Kim JS, Kim WS, Kim H, Kim LH, Kang SM, Park J, Shin SJ, Vaccine efficacy of a
Mycobacterium tuberculosis Beijing-specific proline-glutamic acid (PE) antigen against highly virulent outbreak isolates,
FASEB Journal, 2019, 33(5):6483-6496
Kwon KW, Kim SJ, Kim H, Kim WS, Kang SM, Choi E, Ha SJ, Yoon JH, Shin SJ, IL-15 generates IFN-γ-producing cells
reciprocally expressing lymphoid-myeloid markers during dendritic cell differentiation, International Journal of Biological
Sciences, 2019, 15(2):464-480


특허
Pharmaceutical composition for prevention or treatment of tuberculosis containing mesenchymal stem cells,
10-2015-0045622, 2015. 03. 31
Vaccine composition for tuberculosis containing Rv3131 protein, 10-2015-0050958, 2015. 04. 10
Animal model forming necrotic granuloma for study of tuberculosis and method for producing the same,
10-2015-0055952, 2015. 04. 21
Biomarkers composition for diagnosis of Mycobacterium abscessus complex lung disease, Shin SJ, Koh WJ, Kim SY,
Patent application no. 10-2014-0117831 (09/04/2014)
Vaccine composition for tuberculosis containing Rv3112 protein, Shin SJ, Kim WS, Cho SN, Han SJ, Patent application no.
10-2014-0093510 (07/23/2014)
Vaccine composition for tuberculosis containing MTBK 20620 or MTBK 24820 protein, Shin SJ, Kim WS, Cho SN, Han SJ,
Patent application no. 10-2014-0093499 (07/23/2014)
Composition comprising ADK for preventing or treating sepsis or septic shock, Park YM, Jung ID, Shin SJ, Park JH,
Lee SJ, Patent application no. 10-2014-0048573 (04/23/2014)
COMPOSITION FOR ENHANCING PROTECTIVE EFFICATY OF VACCINE AGAINST TUBERCULOSIS AND THE METHOD
THEREOF, Shin SJ, Kim JS, Kim WS, Cho SN, Patent application no. 10-2014-0027341 (03/07/2014)
Vaccine composition for tuberculosis containing Rv0351 protein, Shin SJ, Kim JS, Kim WS, Cho SN, Han SJ, Patent
application no. 10-2014-0023165 (02/27/2014)
Animal model for the study of granuloma and method for producing the same, Shin SJ, Kim JS, Patent application no.
10-2013-0113197 (09/24/2013)
Composition for inducing maturation of dendritic cell comprising Mycobacterium abscessus MAB1843, Shin SJ,
Park YM, Jung ID, Kim JS, Kim WS, Patent application no. 10-2013-0113193 (09/24/2013)
Compositon for inducing maturation of dendritic cell comprising MAB2560, Park YM, Jung ID, Shin SJ, Patent application no.
10-2013-0014324 (02/08/2013)
Compositon for maturating dendritic cell comprising Mycobacterium tuberculosis Rv2769c, Cho SN, Lee HJ, Shin SJ,
Byun EH, Kim WS, Kim JS, Patent application no. 10-2012-0041665 (04/20/2012)
Compositon for maturating dendritic cell comprising Mycobaccterium paratuberculosis MAP1981c, Shin SJ, Cho SN, Byun EH, Kim WS, Kim JS, Patent application no. 10-2012-0041654 (04/20/2012)
Compositon for inducing maturation of dendritic cell comprising Mycobacterium tuberculosis RpfB, Cho SN, Lee HJ,
Shin SJ, Choi HG, Byun EH, Kim WS, Kim JS, Kim HJ, Patent application no. 10-2012-0013868 (02/10/2012)
COMPOSITION FOR MATURATION OF DENDRITIC CELL COMPRISING Mycobacterium paratuberculosis MAP1305, Park YM,
Jung ID, Shin SJ, Kim WS, Patent application no. 10-2012-0012760 (02/08/2012)
COMPOSITION FOR MATURATION OF DENDRITIC CELL COMPRISING Mycobacterium tuberculosis Rv2005c, Park YM,
Jung ID, Shin SJ, Kim WS, Patent application no. 10-2012-0012297 (02/07/2012)
Maturation method for Dendritic cell using Mycobacterium tuberculosis Rv2299c, Shin SJ, Choi HG, Byun EH, Kim WS,
Kim JS, Kim HJ, Patent application no. 10-2011-0103498 (10/11/2011), Patent registration no. 10-1270999 (05/29/2013)
Method for transformation of Mycobacteria by the modified heat shock protocol with lysozyme, Shin SJ, Whang J, Kim HJ,
Patent application no. 10-2011-0102388 (10/07/2011), Patent registration no. 10-1237255 (02/20/2013)
Maturation method for Dendritic cell using Mycobacterium paratuberculosis MAP1948, Shin SJ, Byun EH, Kim WS, Kim JS,
Kim HJ, Patent application no. 10-2011-0102394 (10/07/2011), Patent registration no. 10-1270997 (05/29/2013)
Compositions for diagnosis of M. abscessus infection, Shin SJ, Kim HJ, Shin AR, Oh JH, Patent application no.
10-2011-0095102 (09/21/2011), Patent registration no. 10-1082816 (11/07/2011)
Maturation method for Dendritic cell using M.tuberculosis Rv0577, Shin SJ, Kim HJ, Byun EH, Kim WS, Kim, Jong Seok,
Patent application no. 10-2011-0073680 (07/25/2011), Patent registration no. 10-1264821 (05/09/2013)
Maturation method for Dendritic cell using Mycobacterium abscessus MAB0981c, Shin SJ, Kim HJ, Byun EH, Kim WS,
Shin AR, Patent application no. 10-2011-0047697 (05/20/2011), Patent registration no. 10-1264811 (05/09/2013)
Maturation method for Dendritic cell using M.tuberculosis Rv0315, Shin SJ, Kim HJ, Byun EH, Kim WS, Patent application no.
10-2011-0021906 (03/11/2011), Patent registration no. 10-1244245 (03/11/2013)
Dendritic cell based cancer medicine using M. tuberculosis Rv0652 protein as an adjuvant, Shin SJ, Jung ID, Park YM,
Kim HJ, Patent application no. 10-2011-0010165 (02/01/2012), Patent registration no. 10-1290230 (07/22/2013)
Vaccine for preventing and treating inflammatory bowel disease comprising Mycobacterium paratuberculosis, Shin SJ,
Min KN, Won CJ, Kim WS, Patent application no. 10-2011-0003830 (01/14/2011), Patent registration no.
10-1296846 (08/08/2013)
Novel Biomarkers For the Serodiagnosis of Crohn’s disease, Cho SN, Shin SJ, Kim HJ, Shin AR, Lee SS, Patent application
no. 10-2011-0003719 (01/13/2011), Patent registration no. 10-1105168 (01/05/2012)
Novel Biomarkers For the Serodiagnosis of Crohn’s disease, Cho SN, Shin SJ, Kim HJ, Shin AR, Lee SS, Patent application
no. 10-2011-0003716 (01/13/2011), Patent registration no. 10-1105163 (01/05/2012)
Novel Biomarkers For the Serodiagnosis of Crohn’s disease, Cho SN, Shin SJ, Kim HJ, Shin AR, Lee SS, Patent application
no. 10-2011-0003713 (01/13/2011), Patent registration no. 10-1105156 (01/05/2012)
A composition for maturation of Dendritic cell containing HspⅩ, Park YM, Jung ID, Shin SJ, Kim HJ, Patent application no.
10-2010-0106773 (10/29/2010), Patent registration no. 10-1172874 (08/03/2012)
A composition for maturation of dendritic cell containing M. tuberculosis RV0351 protein, Shin SJ, Park YM, Jung ID,
Kim HJ, Kim WS, Patent application no. 10-2010-0098571 (10/11/2010), Patent registration no. 10-1221590 (01/07/2013)
Maturation method using M. tuberculosis RV0652 protein for Dendritic cell, Park YM, Jung ID, Shin SJ, Kim HJ, Patent
application no. 10-2010-0046354 (05/18/2010), Patent registration no. 10-1087033 (11/21/2011)
Biomarkers for the serodiagnosis of serodiagnosis of diagnosis of extrapulmonary tuberculosis, Shin SJ, Kim HJ, Shin AR,
Cho SN, Patent application no. 10-2010-0026799 (03/25/2010), Patent registration no. 10-1251041 (03/29/2013)
Dendritic cell based cancer medicine using HBHA as an adjuvant, Park YM, Jung ID, Shin SJ, Kim HJ, Patent application no.
10-2010-0009750 (02/02/2010), Patent registration no. 10-1209416 (11/30/2012)
Maturation method for Dendritic cell using heparin-binding hemagglutin, Park YM, Jung ID, Shin SJ, Kim HJ, Patent
application no. 10-2010-0009747 (02/02/2010), Patent registration no. 10-1052350 (07/21/2011)
Primer pairs for diagnosis of Mycobacterium avium complex and Usage Thereof, Shin SJ, Lee BS, Michael T. Collins
Elizabeth J.B. Manning, Patent application no. 10-2009-0099328 (10/19/2009), Patent registration no.
10-1181371 (09/04/2012)
Composition for diagnosis of M. Tuberculosis and Method for diagnosis using the same, Kim HJ, Shin SJ, Shin AR,
Patent application no. 10-2009-0097508 (10/14/2009), Patent registration no. 10-1135668 (04/04/2012)
Screening Methods for Diagnostic Markers for Mycobacterium abscessus Infection and Protein Antigens, Shin SJ, Kim HJ,
Shin AR, Oh JH, Patent application no. 10-2009-0034587 (04/21/2009), Patent registration no. 10-1140405 (04/19/2012)
Assay for Antibodies to Mycobacterium paratuberculosis, Shin SJ, Collins MT. Application No./Patent No.
07841886.0-1212 / 2084261 (08/19/2009, International patent, EU and USA)
MYCOBACTERIAL CULTURE SCREENING TEST FOR MYCOBACTERIUM AVIUM COMPLEX BACTERIA, Shin SJ,
Collins MT, 09723234.2-1223 / 2265955, (01/11/2011, International patent, EU and USA)
Method for Screening Makers for Diagnosis of Tuberculosis Phase and Protein Antigen, Cho SN, Shin SJ, Jeon BY,
Patent application no. 10-2008-0092934 (09/22/2008), Patent registration no. 10-1045666 (06/24/2011)
Novel Biomarkers For the Serodiagnosis of Crohn’s disease, Cho SN, Shin SJ, Kim HJ, Shin AR, Lee SS, Patent application
no. 10-2008-0062532 (06/30/2008), Patent registration no. 10-1094974 (12/09/2011)
Media for M. tuberculosis -growth enhancer and the Cultivation Method thereof, Cho SN, Shin SJ, Patent application no.
10-2008-0042027 (05/06/2008), Patent registration no. 10-1057053 (08/09/2011)

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